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peptide comparison · metabolic × healing & repair

Retatrutide vs TB-500

Two compounds, mechanism by mechanism. Where they overlap, where they don't, and which vendors stock each.

§ 01

Mechanism

retatrutide

Retatrutide

LY3437943GLP-3triple-G

Triple agonist of GLP-1, GIP, and glucagon receptors. Eli Lilly's Phase 3 candidate (TRIUMPH program).

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vs
tb-500

TB-500

Thymosin Beta-4 fragment

Synthetic fragment of the naturally occurring thymosin beta-4. Researched for cell migration and tissue repair.

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§ 02

Key facts

factRetatrutideTB-500
category
·metabolichealing & repair·
half-life
·~6 days—·
research dosing
·Research literature cites 1–12 mg weekly subcutaneous in dose-escalation studies.Research literature cites 2–5 mg twice weekly for 4–6 weeks.·
trending
search demand
●95/10068/100○
vendors stocking
·11·
aliases
·LY3437943 · GLP-3 · triple-GThymosin Beta-4 fragment·
§ 03

Use-case overlap

only retatrutide
  • weight loss
  • metabolic dysfunction
  • fatty liver
both

none

only tb-500
  • recovery
  • tissue repair
§ 04

Where to buy

retatrutide
Retatrutide
1 verified vendor
Limitless Life Nootropics
See all vendors →
tb-500
TB-500
1 verified vendor
Particle Peptides
See all vendors →
§ 05

Sources

  1. [01]Triple–Hormone-Receptor Agonist Retatrutide for Obesity (NEJM)· Retatrutide
  2. [02]Lilly TRIUMPH Phase 3 announcement· Retatrutide
  3. [03]Thymosin beta 4 and its actin-binding partners· TB-500
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